When Does Depression Require Medication?

Depression affects millions of people worldwide, but not everyone who struggles with it needs medication. Some people benefit from therapy, lifestyle changes, or a combination of approaches. Others may need the support of antidepressants to find relief.

At Nicholson Psychiatry, PLLC, in Bellevue, Washington, Jeanne Nicholson, ARNP, PMHNP-BC, has helped many patients with their depression. She recognizes that understanding when medication helps can make the decision feel less overwhelming.

Mild vs. severe depression

The severity of someone’s depression often guides whether we recommend medication. Mild depression may respond well to talk therapy, lifestyle changes, or support groups. Moderate to severe depression may require medication to balance brain chemicals that impact mood.

If your symptoms interfere with work, relationships, or daily functioning, it may be time to consider professional treatment, including possibly medication.

Signs you might need medication

While every person’s experience is unique, there are common indicators suggesting that medication may help. Consider the following:

Persistent sadness or hopelessness that doesn’t improve
Difficulty sleeping, eating, or focusing
Loss of interest in activities you once enjoyed
Intense fatigue or low energy that makes performing tasks difficult
Thoughts of self-harm or suicide

If these symptoms persist for weeks or months, medication may provide the stability needed to begin healing.

How medication fits into treatment

Medication isn’t a one-size-fits-all solution, and it’s rarely the only step in treatment. Antidepressants are most effective when combined with therapy and healthy lifestyle habits. For example:

Cognitive behavioral therapy (CBT)

This treatment option helps you reframe negative thought patterns.

Lifestyle changes

We highly recommend exercise, nutrition, and sleep routines to support overall mental health.

Stress management

Don’t underestimate the power of practicing mindfulness, relaxation techniques, or journaling.

Deciding on treatment with your provider

The decision to start medication should always be made in consultation with a health care professional. Jeanne Nicholson is here to:

Review your symptoms and medical history
Rule out physical conditions that mimic depression
Discuss the benefits, risks, and possible side effects

For many, starting medication is a turning point in the battle with depression — not a sign of weakness, but a proactive step toward wellness.

In the end, if your depression feels unmanageable or hasn’t improved with other treatment approaches, it may be time to talk with us about whether medication could help.

If you’re ready to learn more, call us at 425-245-5240 or use our online booking tool to schedule your appointment today.